NKTR

NKTR
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2HE9
Identifiers
Aliases	NKTR, p104, natural killer cell triggering receptor
External IDs	OMIM: 161565; MGI: 97346; HomoloGene: 122148; GeneCards: NKTR; OMA:NKTR - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	42,648,735 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	121,756,843 bp
RNA expression pattern
	Top expressed in
	pylorus; ; cardia; ; caput epididymis; ; tail of epididymis; ; optic nerve; ; Achilles tendon; ; corpus epididymis; ; superior surface of tongue; ; visceral pleura; ; corpus callosum;
	Top expressed in
	ascending aorta; ; neural layer of retina; ; aortic valve; ; tail of embryo; ; genital tubercle; ; cerebellar cortex; ; dorsomedial hypothalamic nucleus; ; Rostral migratory stream; ; habenula; ; superior frontal gyrus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	isomerase activity; peptidyl-prolyl cis-trans isomerase activity; cyclosporin A binding; unfolded protein binding;
Cellular component	membrane; nucleoplasm; mitochondrion; cytosol; plasma membrane; nucleus;
Biological process	protein folding; protein peptidyl-prolyl isomerization; protein refolding;
	Sources:Amigo / QuickGO
Orthologs
	4820
	18087
	ENSG00000114857
	ENSMUSG00000032525
	P30414
	P30415
	NM_001012651; NM_005385; NM_001349124; NM_001349125; NM_001349126
	NM_010918
	NP_005376; NP_001336053; NP_001336054; NP_001336055
	NP_035048
	Wikidata
View/Edit Human	View/Edit Mouse

NK-tumor recognition protein is a protein that in humans is encoded by the NKTR gene.

This gene encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain. It is present on the surface of natural killer cells and facilitates their binding to targets. Its expression is regulated by IL2 activation of the cells.