NLRX1

NLRX1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3UN9
Identifiers
Aliases	NLRX1, CLR11.3, DLNB26, NOD26, NOD5, NOD9, NLR family member X1
External IDs	OMIM: 611947; MGI: 2429611; HomoloGene: 11623; GeneCards: NLRX1; OMA:NLRX1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	119,184,016 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	44,179,896 bp
RNA expression pattern
	Top expressed in
	epithelium of esophagus; ; human penis; ; vulva; ; mucosa of pharynx; ; apex of heart; ; gingival epithelium; ; oral cavity; ; muscle of thigh; ; skin of arm; ; triceps brachii muscle;
	Top expressed in
	granulocyte; ; superior surface of tongue; ; gallbladder; ; Ileal epithelium; ; hair follicle; ; ankle joint; ; conjunctival fornix; ; muscle of thigh; ; blood; ; plantaris muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; protein binding; ATP binding;
Cellular component	mitochondrial outer membrane; membrane; mitochondrion; plasma membrane; cell junction; cytoplasm;
Biological process	negative regulation of interleukin-6 production; negative regulation of type I interferon production; viral process; negative regulation of inflammatory response; negative regulation of interferon-beta production; negative regulation of RIG-I signaling pathway; negative regulation of I-kappaB kinase/NF-kappaB signaling; immune system process; negative regulation of innate immune response; innate immune response; intracellular signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	79671
	270151
	ENSG00000160703
	ENSMUSG00000032109
	Q86UT6
	Q3TL44
	NM_001282143; NM_001282144; NM_001282358; NM_024618; NM_170722
	NM_001163742; NM_001163743; NM_178420
	NP_001269072; NP_001269073; NP_001269287; NP_078894
	NP_001157214; NP_001157215; NP_848507
	Wikidata
View/Edit Human	View/Edit Mouse

NLRX1 or NLR family member X1, short for nucleotide-binding oligomerization domain, leucine rich repeat containing X1 is a protein that in humans is encoded by the NLRX1 gene. It is also known as NOD-like receptor X1, NLR family, X1, NOD5, NOD9, and CLR11.3, and is a member of the NOD-like receptor family of pattern recognition receptors.