NMNAT1

NMNAT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1GZU, 1KKU, 1KQN, 1KQO, 1KR2
Identifiers
Aliases	NMNAT1, LCA9, NMNAT, PNAT1, nicotinamide nucleotide adenylyltransferase 1, SHILCA
External IDs	OMIM: 608700; MGI: 1913704; HomoloGene: 39074; GeneCards: NMNAT1; OMA:NMNAT1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	9,985,501 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	149,569,659 bp
RNA expression pattern
	Top expressed in
	muscle of thigh; ; mucosa of transverse colon; ; testicle; ; gastrocnemius muscle; ; islet of Langerhans; ; monocyte; ; Achilles tendon; ; stromal cell of endometrium; ; rectum; ; apex of heart;
	Top expressed in
	otic placode; ; otic vesicle; ; saccule; ; muscle of thigh; ; right kidney; ; quadriceps femoris muscle; ; tibialis anterior muscle; ; skeletal muscle tissue; ; embryo; ; intercostal muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; nucleotidyltransferase activity; protein binding; ATP binding; catalytic activity; nicotinamide-nucleotide adenylyltransferase activity; nicotinate-nucleotide adenylyltransferase activity; identical protein binding;
Cellular component	nucleus; nucleoplasm; nuclear body; cytoplasm;
Biological process	pyridine nucleotide biosynthetic process; NAD metabolic process; NAD biosynthetic process; biosynthesis; 'de novo' NAD biosynthetic process from aspartate; response to wounding; ATP generation from poly-ADP-D-ribose; positive regulation of MAPK cascade; negative regulation of neuron apoptotic process; negative regulation of apoptotic DNA fragmentation; nucleotide biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	64802
	66454
	ENSG00000173614
	ENSMUSG00000028992
	Q9HAN9
	Q9EPA7
	NM_001297778; NM_001297779; NM_022787
	NM_133435; NM_001356357
	NP_001284707; NP_001284708; NP_073624
	NP_597679; NP_001343286
	Wikidata
View/Edit Human	View/Edit Mouse

Nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1) is an enzyme that in humans is encoded by the nmnat1 gene. It is a member of the nicotinamide-nucleotide adenylyltransferases (NMNATs) which catalyze nicotinamide adenine dinucleotide (NAD) synthesis.