NNMT

NNMT
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3ROD, 2IIP
Identifiers
Aliases	NNMT, Nnmt, nicotinamide N-methyltransferase
External IDs	OMIM: 600008; MGI: 1099443; HomoloGene: 4496; GeneCards: NNMT; OMA:NNMT - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	114,313,285 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	48,516,453 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; pericardium; ; vena cava; ; Descending thoracic aorta; ; right lobe of liver; ; Achilles tendon; ; ascending aorta; ; popliteal artery; ; tibial arteries; ; gastric mucosa;
	Top expressed in
	left lobe of liver; ; subcutaneous adipose tissue; ; white adipose tissue; ; intercostal muscle; ; calvaria; ; tunica adventitia of aorta; ; ascending aorta; ; stroma of bone marrow; ; lactiferous gland; ; endothelial cell of lymphatic vessel;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; transferase activity; nicotinamide N-methyltransferase activity; pyridine N-methyltransferase activity;
Cellular component	cytoplasm; cytosol;
Biological process	methylation; animal organ regeneration; response to organonitrogen compound; NAD biosynthesis via nicotinamide riboside salvage pathway;
	Sources:Amigo / QuickGO
Orthologs
	4837
	18113
	ENSG00000166741
	ENSMUSG00000032271
	P40261
	O55239
	NM_006169
	NM_001311062; NM_010924
	NP_006160; NP_001358974; NP_001358975; NP_001358976
	NP_001297991; NP_035054
	Wikidata
View/Edit Human	View/Edit Mouse

Nicotinamide N-methyltransferase (NNMT) is an enzyme that in humans is encoded by the NNMT gene. NNMT catalyzes the methylation of nicotinamide and similar compounds using the methyl donor S-adenosyl methionine (SAM-e) to produce S-adenosyl-L-homocysteine (SAH) and 1-methylnicotinamide.