NOBOX

NOBOX
Identifiers
Aliases	NOBOX, OG-2, OG2, OG2X, POF5, TCAG_12042, NOBOX oogenesis homeobox
External IDs	OMIM: 610934; MGI: 108011; HomoloGene: 51066; GeneCards: NOBOX; OMA:NOBOX - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	144,410,227 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	43,286,488 bp
RNA expression pattern
	Top expressed in
	gonad; ; right testis; ; left testis; ; right ovary; ; left ovary;
	Top expressed in
	primary oocyte; ; zygote; ; secondary oocyte; ; embryo; ; ovary; ; morula; ; morula; ; lens; ; blastocyst; ; epithelium of lens;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	multicellular organism development; cell differentiation; regulation of transcription, DNA-templated; transcription, DNA-templated; oogenesis; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	135935
	18291
	ENSG00000106410; ENSG00000285328
	ENSMUSG00000029736
	O60393
	Q8VIH1
	NM_001080413
	NM_130869
	NP_001073882
	NP_570939
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein NOBOX, also known as newborn ovary homeobox protein, is a protein that in humans is encoded by the NOBOX gene. The official symbol (NOBOX) and the official full name (NOBOX oogenesis homeobox) are maintained by the HGNC. The NOBOX gene is conserved in chimpanzee, Rhesus monkey, cow, mouse, and rat. There are 175 organisms that have orthologs with human gene NOBOX. It is capable of regulating other genes that are important in the development of follicles. Follicles do not develop and oocytes decrease in its absence which lead to infertility.