Neuropeptides B/W receptor 2

NPBWR2
Identifiers
Aliases	NPBWR2, GPR8, Neuropeptides B/W receptor 2, neuropeptides B and W receptor 2
External IDs	OMIM: 600731; HomoloGene: 128565; GeneCards: NPBWR2; OMA:NPBWR2 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	64,107,565 bp
RNA expression pattern
	Top expressed in
	primary visual cortex; ; superior frontal gyrus; ; prefrontal cortex; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; right frontal lobe; ; pituitary gland; ; anterior pituitary; ; anterior cingulate cortex; ; adrenal gland;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled opioid receptor activity; neuropeptide binding; protein binding; G protein-coupled receptor activity; signal transducer activity; neuropeptide receptor activity; peptide binding;
Cellular component	integral component of membrane; neuron projection; plasma membrane; integral component of plasma membrane; membrane;
Biological process	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; neuropeptide signaling pathway; signal transduction; chemical synaptic transmission; G protein-coupled opioid receptor signaling pathway; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	2832
	n/a
	ENSG00000125522; ENSG00000277339
	n/a
	P48146
	n/a
	NM_005286
	n/a
	NP_005277
	n/a
	Wikidata
View/Edit Human

Neuropeptides B/W receptor 2, also known as NPBW2, is a human protein encoded by the NPBWR2 gene.

The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor. The encoded protein is similar in sequence to another G protein-coupled receptor (GPR7), and it is structurally similar to opioid and somatostatin receptors. This protein binds neuropeptides B and W. This gene is intronless and is expressed primarily in the frontal cortex of the brain.