NPLOC4

NPLOC4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2PJH
Identifiers
Aliases	NPLOC4, NPL4, NPL4 homolog, ubiquitin recognition factor
External IDs	OMIM: 606590; MGI: 2679787; HomoloGene: 5403; GeneCards: NPLOC4; OMA:NPLOC4 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	81,648,465 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	120,328,534 bp
RNA expression pattern
	Top expressed in
	gastrocnemius muscle; ; apex of heart; ; muscle of thigh; ; stromal cell of endometrium; ; right testis; ; right coronary artery; ; islet of Langerhans; ; left testis; ; left ventricle; ; right adrenal gland;
	Top expressed in
	spermatocyte; ; muscle of thigh; ; cumulus cell; ; interventricular septum; ; ascending aorta; ; aortic valve; ; spermatid; ; supraoptic nucleus; ; seminiferous tubule; ; lip;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ubiquitin binding; protein binding; metal ion binding; ubiquitin protein ligase binding;
Cellular component	cytoplasm; cytosol; nuclear outer membrane-endoplasmic reticulum membrane network; endoplasmic reticulum; nucleus; UFD1-NPL4 complex; nucleoplasm; VCP-NPL4-UFD1 AAA ATPase complex;
Biological process	error-free translesion synthesis; retrograde protein transport, ER to cytosol; Golgi organization; ubiquitin-dependent ERAD pathway; proteasome-mediated ubiquitin-dependent protein catabolic process; negative regulation of type I interferon production; negative regulation of RIG-I signaling pathway; ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	55666
	217365
	ENSG00000182446
	ENSMUSG00000039703
	Q8TAT6
	P60670
	NM_017921; NM_001369698
	NM_001195023; NM_199469
	NP_060391; NP_001356627; NP_060391.2
	NP_001181952; NP_955763
	Wikidata
View/Edit Human	View/Edit Mouse

Nuclear protein localization protein 4 homolog is a protein that in humans is encoded by the NPLOC4 gene.