NPRL3

NPRL3
Identifiers
Aliases	NPRL3, C16orf35, CGTHBA, HS-40, MARE, NPR3, RMD11, NPR3 like, GATOR1 complex subunit, FFEVF3
External IDs	OMIM: 600928; MGI: 109258; HomoloGene: 8091; GeneCards: NPRL3; OMA:NPRL3 - orthologs
Gene location (Human)
Chr.	Chromosome 16 (human)
End	138,677 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	32,217,707 bp
RNA expression pattern
	Top expressed in
	blood; ; muscle of thigh; ; right uterine tube; ; left ovary; ; right ovary; ; right hemisphere of cerebellum; ; apex of heart; ; right adrenal gland; ; right adrenal cortex; ; right frontal lobe;
	Top expressed in
	muscle of thigh; ; neural layer of retina; ; lip; ; spermatocyte; ; dentate gyrus of hippocampal formation granule cell; ; superior frontal gyrus; ; right kidney; ; primary visual cortex; ; ventricular zone; ; interventricular septum;
	More reference expression data
	n/a
Gene ontology
Molecular function	GTPase activator activity; protein binding;
Cellular component	GATOR1 complex; lysosome; lysosomal membrane; membrane;
Biological process	negative regulation of TOR signaling; cellular response to amino acid starvation; roof of mouth development; ventricular septum development; aorta morphogenesis; cardiac muscle tissue development; positive regulation of GTPase activity; TORC1 signaling; regulation of autophagosome assembly;
	Sources:Amigo / QuickGO
Orthologs
	8131
	17168
	ENSG00000103148
	ENSMUSG00000020289
	Q12980
	Q8VIJ8
NM_001039476; NM_001077350; NM_001243247; NM_001243248; NM_001243249;
	NM_012075
	NM_001284359; NM_001284360; NM_181569
	NP_001034565; NP_001070818; NP_001230176; NP_001230177; NP_001230178
	NP_001271288; NP_001271289; NP_853547
	Wikidata
View/Edit Human	View/Edit Mouse

Nitrogen permease regulator-like 3 is a protein that in humans is encoded by the NPRL3 gene.