NPTXR

NPTXR
Identifiers
Aliases	NPTXR, NPR, neuronal pentraxin receptor
External IDs	OMIM: 609474; MGI: 1920590; HomoloGene: 8620; GeneCards: NPTXR; OMA:NPTXR - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	38,844,028 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	79,688,967 bp
RNA expression pattern
	Top expressed in
	Brodmann area 10; ; frontal pole; ; Region I of hippocampus proper; ; right frontal lobe; ; cingulate gyrus; ; anterior cingulate cortex; ; dorsolateral prefrontal cortex; ; Amygdala; ; Brodmann area 9; ; orbitofrontal cortex;
	Top expressed in
	piriform cortex; ; subiculum; ; dentate gyrus of hippocampal formation granule cell; ; primary visual cortex; ; anterior amygdaloid area; ; superior frontal gyrus; ; habenula; ; primary motor cortex; ; cingulate gyrus; ; medial dorsal nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding;
Cellular component	membrane; integral component of membrane; plasma membrane; cytoplasmic side of plasma membrane; filopodium; dendrite; growth cone; soma; glutamatergic synapse;
Biological process	neuron projection development; regulation of postsynaptic neurotransmitter receptor activity;
	Sources:Amigo / QuickGO
Orthologs
	23467
	73340
	ENSG00000221890
	ENSMUSG00000022421
	O95502
	Q99J85
	NM_058178; NM_014293
	NM_030689
	NP_055108
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Neuronal pentraxin receptor is a protein that in humans is encoded by the NPTXR gene.

This gene encodes a protein similar to the rat neuronal pentraxin receptor. The rat protein pentraxin is thought to mediate neuronal uptake of synaptic material and the presynaptic snake venom toxin, taipoxin. Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon. This may also be true for human and mouse, based on strong sequence conservation amongst these species.