Photoreceptor cell-specific nuclear receptor

NR2E3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4LOG
Identifiers
Aliases	NR2E3, Nr2e3, A930035N01Rik, PNR, RNR, rd7, ESCS, RP37, nuclear receptor subfamily 2 group E member 3
External IDs	OMIM: 604485; MGI: 1346317; HomoloGene: 84397; GeneCards: NR2E3; OMA:NR2E3 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	71,818,259 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	59,867,942 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; testicle; ; secondary oocyte; ; gonad; ; retinal pigment epithelium; ; right uterine tube; ; tendon of biceps brachii; ; prostate; ; fundus; ; Descending thoracic aorta;
	Top expressed in
	neural layer of retina; ; outer nuclear layer; ; retinal pigment epithelium; ; epithelium of lens; ; zygote; ; embryo; ; epithelium of small intestine; ; secondary oocyte; ; primary oocyte; ; ileum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; zinc ion binding; metal ion binding; steroid hormone receptor activity; nuclear receptor activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; sequence-specific DNA binding;
Cellular component	transcription regulator complex; nucleoplasm; nucleus;
Biological process	phototransduction; regulation of transcription, DNA-templated; response to stimulus; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; transcription, DNA-templated; retina development in camera-type eye; eye photoreceptor cell development; transcription initiation from RNA polymerase II promoter; negative regulation of cell population proliferation; steroid hormone mediated signaling pathway; signal transduction; visual perception; intracellular receptor signaling pathway; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	10002
	23958
	ENSG00000278570
	ENSMUSG00000032292
	Q9Y5X4
	Q9QXZ7
	NM_001281446; NM_014249; NM_016346
	NM_013708
	NP_055064; NP_057430
	NP_038736
	Wikidata
View/Edit Human	View/Edit Mouse

The photoreceptor cell-specific nuclear receptor (PNR), also known as NR2E3 (nuclear receptor subfamily 2, group E, member 3), is a protein that in humans is encoded by the NR2E3 gene. PNR is a member of the nuclear receptor super family of intracellular transcription factors.