Diadenosine hexaphosphate hydrolase (AMP-forming)
| Diadenosine hexaphosphate hydrolase (AMP-forming) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.6.1.60 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Diadenosine hexaphosphate hydrolase (AMP-forming) (EC 3.6.1.60, hAps1, NUDT11 (gene), hAps2, NUDT10 (gene)) is an enzyme with systematic name P1,P6-bis(5'-adenosyl)hexaphosphate nucleotidohydrolase (AMP-forming). This enzyme catalyses the following chemical reaction
- (1) P1,P6-bis(5'-adenosyl)hexaphosphate + H2O adenosine 5'-pentaphosphate + AMP
- (2) P1,P5-bis(5'-adenosyl)pentaphosphate + H2O adenosine 5'-tetraphosphate + AMP
A divalent cation is essential for activity.