NUDT11

NUDT11
Identifiers
Aliases	NUDT11, APS1, ASP1, DIPP3b, DIPP3beta, hDIPP3beta, nudix hydrolase 11
External IDs	OMIM: 300528; MGI: 1930957; HomoloGene: 86995; GeneCards: NUDT11; OMA:NUDT11 - orthologs
EC number	3.6.1.60
Gene location (Human)
Chr.	X chromosome (human)
End	51,496,592 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	5,967,164 bp
RNA expression pattern
	Top expressed in
	orbitofrontal cortex; ; Brodmann area 23; ; embryo; ; ganglionic eminence; ; middle temporal gyrus; ; gonad; ; right testis; ; superior frontal gyrus; ; oocyte; ; secondary oocyte;
	Top expressed in
	arcuate nucleus; ; dorsomedial hypothalamic nucleus; ; median eminence; ; ventromedial nucleus; ; suprachiasmatic nucleus; ; paraventricular nucleus of hypothalamus; ; barrel cortex; ; supraoptic nucleus; ; yolk sac; ; ventral tegmental area;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity; inositol diphosphate tetrakisphosphate diphosphatase activity; inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; hydrolase activity; metal ion binding; inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity; inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity; inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity; inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity; inositol diphosphate pentakisphosphate diphosphatase activity; inositol bisdiphosphate tetrakisphosphate diphosphatase activity; endopolyphosphatase activity; diphosphoinositol-polyphosphate diphosphatase activity; bis(5'-adenosyl)-hexaphosphatase activity; bis(5'-adenosyl)-pentaphosphatase activity; m7G(5')pppN diphosphatase activity;
Cellular component	intracellular anatomical structure; nucleus; cytoplasm; cytosol;
Biological process	inositol phosphate metabolic process; diphosphoinositol polyphosphate metabolic process; diadenosine pentaphosphate catabolic process; diadenosine hexaphosphate catabolic process; adenosine 5'-(hexahydrogen pentaphosphate) catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	55190
	58242
	ENSG00000196368
	ENSMUSG00000073295
	Q96G61
	P0C027; P0C028
	NM_018159
	NM_021431
	NP_060629
	NP_001026834; NP_067406; NP_067406
	Wikidata
View/Edit Human	View/Edit Mouse

Diphosphoinositol polyphosphate phosphohydrolase 3-beta is an enzyme that in humans is encoded by the NUDT11 gene.

NUDT11 belongs to a subgroup of phosphohydrolases that preferentially attack diphosphoinositol polyphosphates.