Nucleoporin 210kDa

Nucleoporin 210kDa
Identifiers
Aliases	NUP210, Nup210, GP210, POM210, nucleoporin 210kDa, nucleoporin 210
External IDs	OMIM: 607703; MGI: 1859555; HomoloGene: 41286; GeneCards: NUP210; OMA:NUP210 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	13,420,309 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	91,093,811 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; lymph node; ; bone marrow cells; ; buccal mucosa cell; ; thymus; ; spleen; ; blood; ; appendix; ; parotid gland; ; mononuclear cell;
	Top expressed in
	mesenteric lymph nodes; ; fetal liver hematopoietic progenitor cell; ; tibiofemoral joint; ; spleen; ; blood; ; thymus; ; human fetus; ; hair follicle; ; bone marrow; ; Paneth cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein dimerization activity;
Cellular component	nuclear membrane; integral component of membrane; nucleus; nuclear envelope; membrane; endoplasmic reticulum; endoplasmic reticulum membrane; nuclear pore; host cell;
Biological process	mitotic nuclear membrane disassembly; viral transcription; viral process; protein sumoylation; protein transport; mRNA transport; regulation of cellular response to heat; intracellular transport of virus; mRNA export from nucleus; tRNA export from nucleus; regulation of gene silencing by miRNA; regulation of glycolytic process; transport;
	Sources:Amigo / QuickGO
Orthologs
	23225
	54563
	ENSG00000132182
	ENSMUSG00000030091
	Q8TEM1
	Q9QY81
	NM_024923
	NM_018815
	NP_079199
	NP_061285
	Wikidata
View/Edit Human	View/Edit Mouse

Nuclear pore glycoprotein-210 (gp210) is an essential trafficking regulator in the eukaryotic nuclear pore complex. Gp-210 anchors the pore complex to the nuclear membrane. and protein tagging reveals its primarily located on the luminal side of double layer membrane at the pore. A single polypeptide motif of gp210 is responsible for sorting to nuclear membrane, and indicate the carboxyl tail of the protein is oriented toward the cytoplasmic side of the membrane.