Nucleoporin 43

NUP43
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4I79, 5A9Q
Identifiers
Aliases	NUP43, bA350J20.1, p42, nucleoporin 43kDa, nucleoporin 43
External IDs	OMIM: 608141; MGI: 1917162; HomoloGene: 11639; GeneCards: NUP43; OMA:NUP43 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	149,749,665 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	7,554,645 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; seminal vesicula; ; oral cavity; ; pylorus; ; hair follicle; ; parietal pleura; ; visceral pleura; ; renal medulla; ; germinal epithelium;
	Top expressed in
	epiblast; ; primary oocyte; ; tail of embryo; ; embryo; ; genital tubercle; ; secondary oocyte; ; embryo; ; morula; ; blastocyst; ; zygote;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytosol; nuclear envelope; nuclear pore; chromosome; chromosome, centromeric region; nucleus; kinetochore; nuclear pore outer ring; host cell;
Biological process	mRNA transport; chromosome segregation; cell division; protein transport; cell cycle; viral process; mRNA export from nucleus; regulation of glycolytic process; tRNA export from nucleus; protein sumoylation; viral transcription; regulation of gene silencing by miRNA; intracellular transport of virus; regulation of cellular response to heat;
	Sources:Amigo / QuickGO
Orthologs
	348995
	69912
	ENSG00000120253
	ENSMUSG00000040034
	Q8NFH3
	P59235
	NM_024647; NM_198887
	NM_145706
	NP_942590
	NP_663752
	Wikidata
View/Edit Human	View/Edit Mouse

Nucleoporin 43 (Nup43) is a protein that in humans is encoded by the NUP43 gene.

Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004).[supplied by OMIM] Along with other nucleoporins.