Neurocan

NCAN
Identifiers
Aliases	NCAN, CSPG3, neurocan
External IDs	OMIM: 600826; MGI: 104694; HomoloGene: 3229; GeneCards: NCAN; OMA:NCAN - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	19,252,233 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	70,573,523 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; Region I of hippocampus proper; ; postcentral gyrus; ; superior frontal gyrus; ; middle frontal gyrus; ; entorhinal cortex; ; Brodmann area 46; ; frontal pole; ; Brodmann area 10;
	Top expressed in
	ganglionic eminence; ; ventricular zone; ; olfactory bulb; ; Rostral migratory stream; ; olfactory tubercle; ; prefrontal cortex; ; barrel cortex; ; nucleus accumbens; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; hyaluronic acid binding; carbohydrate binding; extracellular matrix structural constituent;
Cellular component	Golgi lumen; extracellular region; lysosomal lumen; extracellular matrix;
Biological process	chondroitin sulfate catabolic process; skeletal system development; central nervous system development; chondroitin sulfate biosynthetic process; extracellular matrix organization; dermatan sulfate biosynthetic process; cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	1463
	13004
	ENSG00000130287
	ENSMUSG00000002341
	O14594
	P55066
	NM_004386
	NM_007789
	NP_004377
	NP_031815
	Wikidata
View/Edit Human	View/Edit Mouse

Neurocan core protein is a protein that in humans is encoded by the NCAN gene.

Neurocan is a member of the lectican / chondroitin sulfate proteoglycan protein families and consists of neurocan core protein and chondroitin sulfate. It is thought to be involved in the modulation of cell adhesion and migration.