Niflumic acid

Niflumic acid
Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	M01AX02 (WHO) M02AA17 (WHO);
Pharmacokinetic data
Elimination half-life	2.5 hr
Identifiers
	IUPAC name 2-{[3-(trifluoromethyl)phenyl]amino}nicotinic acid;
CAS Number	4394-00-7 ;
PubChem CID	4488;
IUPHAR/BPS	2439;
ChemSpider	4333 ;
UNII	4U5MP5IUD8;
KEGG	D08275 ;
ChEMBL	ChEMBL63323 ;
CompTox Dashboard (EPA)	DTXSID1023368 ;
ECHA InfoCard	100.022.289
Chemical and physical data
Formula	C13H9F3N2O2
Molar mass	282.222 g·mol−1
3D model (JSmol)	Interactive image;
Melting point	204 °C (399 °F)
	SMILES C1=CC(=CC(=C1)NC2=C(C=CC=N2)C(=O)O)C(F)(F)F;
	InChI InChI=1S/C13H9F3N2O2/c14-13(15,16)8-3-1-4-9(7-8)18-11-10(12(19)20)5-2-6-17-11/h1-7H,(H,17,18)(H,19,20) ; Key:JZFPYUNJRRFVQU-UHFFFAOYSA-N ;
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Niflumic acid is a drug used for joint and muscular pain. It is categorized as an inhibitor of cyclooxygenase-2. In experimental biology, it has been employed to inhibit chloride channels. It has also been reported to act on GABA-A and NMDA channels and to block T-type calcium channels.