Non-Hodgkin lymphoma

Non-Hodgkin lymphoma
Other namesNon-Hodgkin disease
Micrograph of mantle cell lymphoma, a type of non-Hodgkin lymphoma. Terminal ileum. H&E stain.
SpecialtyHematology and oncology
SymptomsEnlarged lymph nodes, fever, night sweats, weight loss, tiredness, itching
Usual onset65–75 years old
Risk factorsPoor immune function, autoimmune diseases, Helicobacter pylori infection, hepatitis C, obesity, Epstein-Barr virus infection
Diagnostic methodBone marrow or lymph node biopsy
TreatmentChemotherapy, radiation, immunotherapy, targeted therapy, stem cell transplantation, surgery, watchful waiting
PrognosisFive-year survival rate 71% (USA)
Frequency4.3 million (affected during 2015)
Deaths231,400 (2015)

Non-Hodgkin lymphoma (NHL), also known as non-Hodgkin's lymphoma, is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas. Symptoms include enlarged lymph nodes, fever, night sweats, weight loss, and tiredness. Other symptoms may include bone pain, chest pain, or itchiness. Some forms are slow-growing while others are fast-growing. Unlike Hodgkin lymphoma, which spreads contiguously, NHL is largely a systemic illness.