RANBP2

RANBP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1RRP, 1XKE, 1Z5S, 3UIN, 3UIO, 3UIP, 4I9Y, 4L6E, 4LQW, 5CLL, 5CLQ, 2LAS
Identifiers
Aliases	RANBP2, ADANE, ANE1, IIAE3, NUP358, TRP1, TRP2, RAN binding protein 2
External IDs	OMIM: 601181; MGI: 894323; HomoloGene: 136803; GeneCards: RANBP2; OMA:RANBP2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	108,785,809 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	58,330,178 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; sperm; ; mucosa of paranasal sinus; ; Skeletal muscle tissue of rectus abdominis; ; epithelium of nasopharynx; ; tibia; ; visceral pleura; ; superficial temporal artery; ; seminal vesicula; ; germinal epithelium;
	Top expressed in
	human fetus; ; Gonadal ridge; ; lobe of cerebellum; ; lacrimal gland; ; cerebellar vermis; ; spermatocyte; ; spermatid; ; left lung lobe; ; primitive streak; ; pineal gland;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	peptidyl-prolyl cis-trans isomerase activity; metal ion binding; ligase activity; protein binding; RNA binding; SUMO transferase activity; GTPase activator activity; protein-containing complex binding; cyclosporin A binding; transferase activity;
Cellular component	cytosol; nuclear membrane; membrane; nuclear pore; nuclear inclusion body; nuclear pore nuclear basket; nucleus; nuclear envelope; lamellae anulatae; intracellular membrane-bounded organelle; cytoplasm; centrosome; mitochondrion; nuclear pore cytoplasmic filaments; cytoplasmic periphery of the nuclear pore complex; host cell;
Biological process	mRNA transport; viral transcription; intracellular transport; protein sumoylation; protein peptidyl-prolyl isomerization; mitotic nuclear membrane disassembly; protein folding; regulation of cellular response to heat; protein transport; viral process; NLS-bearing protein import into nucleus; intracellular transport of virus; mRNA export from nucleus; tRNA export from nucleus; sister chromatid cohesion; centrosome localization; G1 phase; RNA export from nucleus; ubiquitin-dependent protein catabolic process; spindle organization; positive regulation of GTPase activity; positive regulation of mitotic centrosome separation; response to amphetamine; positive regulation of glucokinase activity; regulation of gene silencing by miRNA; regulation of glycolytic process; transport; regulation of gluconeogenesis;
	Sources:Amigo / QuickGO
Orthologs
	5903
	19386
	ENSG00000153201
	ENSMUSG00000003226
	P49792
	Q9ERU9
	NM_006267
	NM_011240
	NP_006258
	NP_035370
	Wikidata
View/Edit Human	View/Edit Mouse

RAN binding protein 2 (RANBP2) is protein which in humans is encoded by the RANBP2 gene. It is also known as nucleoporin 358 (Nup358) since it is a member nucleoporin family that makes up the nuclear pore complex. RanBP2 has a mass of 358 kDa.