OLA1

OLA1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2OHF
Identifiers
Aliases	OLA1, DOC45, GBP45, GTBP9, GTPBP9, PTD004, Obg-like ATPase 1, Obg like ATPase 1
External IDs	OMIM: 611175; MGI: 1914309; HomoloGene: 5361; GeneCards: OLA1; OMA:OLA1 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	174,248,599 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	73,049,268 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; ganglionic eminence; ; lateral nuclear group of thalamus; ; Pons; ; Brodmann area 23; ; gingival epithelium; ; lactiferous duct; ; parotid gland; ; entorhinal cortex; ; ventricular zone;
	Top expressed in
	Paneth cell; ; tail of embryo; ; cumulus cell; ; condyle; ; ureter; ; medial ganglionic eminence; ; primitive streak; ; epiblast; ; barrel cortex; ; hair follicle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; hydrolase activity; metal ion binding; ATP binding; ATPase activity; cadherin binding; ribosome binding; ribosomal large subunit binding;
Cellular component	centrosome; nucleolus; extracellular exosome; membrane; nucleus; extracellular region; cytoplasm; cytosol; platelet alpha granule lumen;
Biological process	ATP metabolic process; platelet degranulation;
	Sources:Amigo / QuickGO
Orthologs
	29789
	67059
	ENSG00000138430
	ENSMUSG00000027108
	Q9NTK5
	Q9CZ30
	NM_013341; NM_001011708; NM_001328688
	NM_025942; NM_030091
	NP_001011708; NP_001315617; NP_037473
	NP_080218; NP_084367
	Wikidata
View/Edit Human	View/Edit Mouse

Obg-like ATPase 1 is an enzyme that in humans is encoded by the OLA1 gene. Ola1 belongs to the protein family of Obg-like GTPases but defines an exceptional example of a protein that has evolved altered nucleotide specificity and binds adenosine triphosphate (ATP) with higher affinity than guanosine triphosphate (GTP).