OLR1

OLR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1YPO, 1YPQ, 1YPU, 1YXJ, 1YXK, 3VLG
Identifiers
Aliases	OLR1, CLEC8A, LOX1, LOXIN, SCARE1, SLOX1, oxidized low density lipoprotein receptor 1
External IDs	OMIM: 602601; MGI: 1261434; HomoloGene: 1910; GeneCards: OLR1; OMA:OLR1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	10,172,138 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	129,484,128 bp
RNA expression pattern
	Top expressed in
	right lung; ; C1 segment; ; bone marrow cells; ; upper lobe of left lung; ; lower lobe of lung; ; placenta; ; corpus callosum; ; testicle; ; appendix; ; gallbladder;
	Top expressed in
	gastrula; ; decidua; ; granulocyte; ; right lung lobe; ; embryo; ; tibiofemoral joint; ; primordial ventricle; ; blastocyst; ; uterus; ; bone marrow;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; carbohydrate binding; identical protein binding;
Cellular component	integral component of membrane; membrane; intracellular membrane-bounded organelle; receptor complex; plasma membrane; integral component of plasma membrane; nucleoplasm; extracellular region; membrane raft; specific granule membrane; tertiary granule membrane;
Biological process	immune system process; blood circulation; proteolysis; cell adhesion; inflammatory response; leukocyte migration; neutrophil degranulation;
	Sources:Amigo / QuickGO
Orthologs
	4973
	108078
	ENSG00000173391
	ENSMUSG00000030162
	P78380
	Q9EQ09
	NM_001172632; NM_001172633; NM_002543
	NM_001301094; NM_001301096; NM_138648
	NP_001166103; NP_001166104; NP_002534
	NP_001288023; NP_001288025; NP_619589
	Wikidata
View/Edit Human	View/Edit Mouse

Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) also known as lectin-type oxidized LDL receptor 1 (LOX-1) is a protein that in humans is encoded by the OLR1 gene.

LOX-1 is the main receptor for oxidized LDL on endothelial cells, macrophages, smooth muscle cells, and other cell types. But minimally oxidized LDL is more readily recognized by the TLR4 receptor, and highly oxidized LDL is more readily recognized by the CD36 receptor.