ORC1

ORC1
Identifiers
Aliases	ORC1, HSORC1L, PARC1, origin recognition complex subunit 1
External IDs	OMIM: 601902; MGI: 1328337; HomoloGene: 31221; GeneCards: ORC1; OMA:ORC1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	52,404,423 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	108,472,030 bp
RNA expression pattern
	Top expressed in
	testicle; ; ventricular zone; ; gonad; ; ganglionic eminence; ; bone marrow; ; mucosa of transverse colon; ; secondary oocyte; ; rectum; ; stromal cell of endometrium; ; bone marrow cells;
	Top expressed in
	zygote; ; secondary oocyte; ; primary oocyte; ; epiblast; ; tail of embryo; ; genital tubercle; ; primitive streak; ; embryo; ; embryo; ; blastocyst;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; nucleotide binding; chromatin binding; protein binding; ATP binding; DNA replication origin binding; metal ion binding;
Cellular component	nuclear origin of replication recognition complex; plasma membrane; nucleolus; origin recognition complex; nucleus; nucleoplasm; cytosol;
Biological process	G1 phase; DNA replication; regulation of transcription involved in G1/S transition of mitotic cell cycle; DNA replication initiation; G1/S transition of mitotic cell cycle; mitotic cell cycle; mitotic DNA replication checkpoint signaling;
	Sources:Amigo / QuickGO
Orthologs
	4998
	18392
	ENSG00000085840
	ENSMUSG00000028587
	Q13415
	Q9Z1N2
	NM_001190818; NM_001190819; NM_004153
	NM_001014425; NM_011015
	NP_001177747; NP_001177748; NP_004144
	NP_035145
	Wikidata
View/Edit Human	View/Edit Mouse

Origin recognition complex subunit 1 is a protein that in humans is encoded by the ORC1 gene. It is closely related to CDC6, and both are the same protein in archaea.