OXSR1

OXSR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2V3S, 2VWI, 3DAK
Identifiers
Aliases	OXSR1, OSR1, oxidative stress responsive 1, oxidative stress responsive kinase 1
External IDs	OMIM: 604046; MGI: 1917378; HomoloGene: 31288; GeneCards: OXSR1; OMA:OXSR1 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	38,255,484 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	119,151,493 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; Skeletal muscle tissue of rectus abdominis; ; mucosa of pharynx; ; body of tongue; ; saphenous vein; ; gastrocnemius muscle; ; embryo; ; ganglionic eminence; ; glutes; ; ventricular zone;
	Top expressed in
	muscle of thigh; ; skeletal muscle tissue; ; genital tubercle; ; quadriceps femoris muscle; ; cumulus cell; ; tail of embryo; ; knee joint; ; triceps brachii muscle; ; ankle; ; medullary collecting duct;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	magnesium ion binding; protein kinase activity; protein binding; kinase activity; metal ion binding; nucleotide binding; transferase activity; ATP binding; protein serine/threonine kinase activity; identical protein binding; protein kinase binding;
Cellular component	extracellular exosome; cytoplasm; cytosol;
Biological process	response to oxidative stress; negative regulation of potassium ion transmembrane transport; cellular hypotonic response; phosphorylation; negative regulation of potassium ion transmembrane transporter activity; protein phosphorylation; peptidyl-threonine phosphorylation; intracellular signal transduction; regulation of mitotic cell cycle; signal transduction; stress-activated protein kinase signaling cascade; activation of protein kinase activity; regulation of apoptotic process; osmosensory signaling pathway; positive regulation of T cell chemotaxis; chemokine (C-C motif) ligand 21 signaling pathway; chemokine (C-X-C motif) ligand 12 signaling pathway; protein autophosphorylation; cellular response to chemokine;
	Sources:Amigo / QuickGO
Orthologs
	9943
	108737
	ENSG00000172939
	ENSMUSG00000036737
	O95747
	Q6P9R2
	NM_005109
	NM_133985; NM_001359582
	NP_005100
	NP_598746; NP_001346511
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase OSR1 is an enzyme that in humans is encoded by the OXSR1 gene.

The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton.