Oxytocin receptor

OXTR
Identifiers
Aliases	OXTR, OT-R, oxytocin receptor
External IDs	OMIM: 167055; MGI: 109147; HomoloGene: 20255; GeneCards: OXTR; OMA:OXTR - orthologs
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	112,466,904 bp
RNA expression pattern
	n/a
	Top expressed in
	mammary gland; ; lumbar subsegment of spinal cord; ; cervix; ; white adipose tissue; ; islet of Langerhans; ; ciliary body; ; pineal gland; ; mesenteric lymph nodes; ; dentate gyrus of hippocampal formation granule cell; ; adrenal gland;
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; peptide binding; signal transducer activity; peptide hormone binding; vasopressin receptor activity; oxytocin receptor activity;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane; intracellular anatomical structure; microvillus; apical plasma membrane;
Biological process	response to cocaine; positive regulation of synapse assembly; positive regulation of norepinephrine secretion; response to cytokine; maternal process involved in parturition; response to estradiol; muscle contraction; response to anoxia; response to organic cyclic compound; eating behavior; ejaculation; estrous cycle; positive regulation of cytosolic calcium ion concentration; response to progesterone; response to amphetamine; ERK1 and ERK2 cascade; regulation of systemic arterial blood pressure by vasopressin; response to steroid hormone; response to peptide hormone; negative regulation of gastric acid secretion; memory; positive regulation of synaptic transmission, GABAergic; response to peptide; heart development; cell surface receptor signaling pathway; telencephalon development; sleep; cellular response to hormone stimulus; positive regulation of blood pressure; positive regulation of synaptic transmission, glutamatergic; Maternal behavior; positive regulation of vasoconstriction; social behavior; positive regulation of penile erection; lactation; digestive tract development; regulation of digestive system process; signal transduction; positive regulation of uterine smooth muscle contraction; suckling behavior; female pregnancy; G protein-coupled receptor signaling pathway; positive regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologs
	5021
	18430
	ENSG00000180914
	ENSMUSG00000049112
	P30559
	P97926
	NM_000916
	NM_001081147
	NP_000907; NP_001341582; NP_001341583; NP_001341584; NP_001341585
	NP_001074616
	Wikidata
View/Edit Human	View/Edit Mouse

The oxytocin receptor, also known as OXTR, is a protein which functions as receptor for the hormone and neurotransmitter oxytocin. In humans, the oxytocin receptor is encoded by the OXTR gene which has been localized to human chromosome 3p25.