Ohio State Route 60

State Route 60 (SR 60) is a north–south state highway that runs the entire length of the U.S. state of Ohio, from the Williamstown Bridge over the Ohio River in Marietta to U.S. Route 6 (US 6) near Lake Erie in Vermilion. It is the seventh longest state route in Ohio.

Heading south from Vermilion, SR 60 traverses rural North Central Ohio while connecting Vermilion, New London, Ashland, and Loudonville. South of Loudonville, SR 60 enters more hilly country, before entering the Muskingum River Valley at Dresden. It closely parallels the Muskingum River for the remainder of its journey to Marietta except for an eleven-mile (18 km) stretch in Morgan County where it moves inland to avoid bends in the river.

Markers for SR 60 are not posted south of the Greene Street/3rd Street intersection in Marietta. SR 60 is unsigned along SR 7 / Greene Street and the Williamstown Bridge approach.