Oncostatin M receptor

OSMR
Identifiers
Aliases	OSMR, OSMRB, PLCA1, IL-31R-beta, IL-31RB, oncostatin M receptor, OSMRbeta
External IDs	OMIM: 601743; MGI: 1330819; HomoloGene: 2972; GeneCards: OSMR; OMA:OSMR - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	38,945,596 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	6,904,450 bp
RNA expression pattern
	Top expressed in
	pericardium; ; saphenous vein; ; cartilage tissue; ; tibia; ; lower lobe of lung; ; right ventricle; ; peritoneum; ; visceral pleura; ; parietal pleura; ; superficial temporal artery;
	Top expressed in
	retinal pigment epithelium; ; transitional epithelium of urinary bladder; ; conjunctival fornix; ; stroma of bone marrow; ; gastrula; ; lumbar spinal ganglion; ; endothelial cell of lymphatic vessel; ; ciliary body; ; right lung lobe; ; tunica media of zone of aorta;
	More reference expression data
	n/a
Gene ontology
Molecular function	cytokine receptor activity; oncostatin-M receptor activity; growth factor binding; cytokine binding; protein binding;
Cellular component	integral component of membrane; oncostatin-M receptor complex; plasma membrane; apical plasma membrane; membrane; external side of plasma membrane; receptor complex;
Biological process	positive regulation of acute inflammatory response; response to cytokine; oncostatin-M-mediated signaling pathway; positive regulation of cell population proliferation; cytokine-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	9180
	18414
	ENSG00000145623
	ENSMUSG00000022146
	Q99650
	O70458
NM_001168355; NM_003999; NM_001323504; NM_001323505; NM_001323506;
	NM_001323507
	NM_011019; NM_001310469
NP_001161827; NP_001310433; NP_001310434; NP_001310435; NP_001310436;
	NP_003990
	NP_001297398; NP_035149
	Wikidata
View/Edit Human	View/Edit Mouse

Oncostatin-M specific receptor subunit beta also known as the Oncostatin M receptor (OSMR) , is one of the receptor proteins for oncostatin M, that in humans is encoded by the OSMR gene.

OSMR is a member of the type I cytokine receptor family. This protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events.