Oxilofrine

Oxilofrine
Clinical data
Trade names	Carnigen, Cophylac, Suprifen, others
Other names	Oxilophrine; Hydroxyephedrine; (±)-Hydroxyephedrine; 4-Hydroxyephedrine; p-Hydroxyephedrine; Oxyephedrine; Methylsynephrine; 4-HMP; 4,β-Dihydroxy-N-methyl-α-methylphenethylamine; 4,β-Dihydroxy-N-methylamphetamine
Routes of; administration	Oral
ATC code	None;
Legal status
Legal status	BR: Class A3 (Psychoactive drugs); US: Unapproved "New Drug" (as defined by 21 U.S. Code § 321(p)(1)). Use in dietary supplements, food, or medicine is unlawful; otherwise uncontrolled.;
Identifiers
	IUPAC name (1S,2R)-(±)-4-(1-Hydroxy-2-methylamino-propyl)phenol;
CAS Number	365-26-4 ;
PubChem CID	9701;
DrugBank	DB11610 ;
ChemSpider	9320 ;
UNII	F49638UBDR;
KEGG	D08314 ;
ChEMBL	ChEMBL30400 ;
CompTox Dashboard (EPA)	DTXSID30110025 ;
ECHA InfoCard	100.006.067
Chemical and physical data
Formula	C10H15NO2
Molar mass	181.235 g·mol−1
	InChI InChI=1S/C10H15NO2/c1-7(11-2)10(13)8-3-5-9(12)6-4-8/h3-7,10-13H,1-2H3 ; Key:OXFGTKPPFSCSMA-UHFFFAOYSA-N ;
	(verify)

Oxilofrine, sold under the brand names Carnigen and Suprifen among others, is a sympathomimetic medication which has been used as an antihypotensive agent and cough suppressant. It is taken by mouth.

Oxilofrine acts as a norepinephrine releasing agent and hence is an indirectly acting sympathomimetic. It is a substituted amphetamine and is closely related to ephedrine (with oxilofrine also being known as 4-hydroxyephedrine).

Oxilofrine was first developed in the 1930s. It is mostly no longer marketed today.