P-Chlorocresol
| Names | |
|---|---|
| Preferred IUPAC name
 4-Chloro-3-methylphenol  | |
| Other names
 p-chloro-m-cresol; PCMC; Preventol; CMK  | |
| Identifiers | |
3D model (JSmol)  | 
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
| ECHA InfoCard | 100.000.392 | 
| EC Number | 
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| KEGG | |
PubChem CID  | 
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| RTECS number | 
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| UNII | |
| UN number | 2669 | 
CompTox Dashboard (EPA)  | 
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| Properties | |
| C7H7ClO | |
| Molar mass | 142.58 g·mol−1 | 
| Appearance | White solid | 
| Odor | Phenolic | 
| Density | 1.37 g/cm3 (20 °C) | 
| Melting point | 55.55 °C (131.99 °F; 328.70 K) | 
| Boiling point | 235 °C (455 °F; 508 K) | 
| 3.8 g/L at 20 °C (in water) | |
| Hazards | |
| GHS labelling: | |
| Danger | |
| H302, H314, H317, H335, H400, H412 | |
| P260, P261, P264, P270, P271, P272, P273, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P330, P333+P313, P363, P391, P403+P233, P405, P501 | |
| Flash point | 118 °C (244 °F; 391 K) | 
| Related compounds | |
Related compounds  | 
Chloroxylenol (4-chloro-3,5-dimethylphenol) | 
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). 
Infobox references  | |
p-Chlorocresol, or 4-chloro-3-methylphenol (ClC6H3CH3OH), also known as p-chloro-m-cresol, is a potent disinfectant and antiseptic. It appears as a pinkish white crystalline solid. It is also used as a preservative in cosmetics and medicinal products for both humans and animals. It is used as an active ingredient in some preparations of veterinary medicines for topical, oral and parenteral use. Normally, the concentration of p-Chlorocresol in oral and parenteral veterinary products are 0.1-0.2%. Concentrations are higher (~0.5%) in topical veterinary products. p-Chlorocresol contains microbial activity against both gram positive and gram negative bacteria and fungi.
The use of p-Chlorocresol is regulated by government agencies such as the US Food and Drug administration, and limits are set on the amount of p-Chlorocresol that can be present in various products.
Chlorocresol was first introduced as a bactericide in 1897 by Kalle & Co. after scientists gradually discovered that more substituted and more lipophylic phenols are less toxic, less irritant and more powerful.