P-Chlorocresol

p-Chlorocresol
Names
Preferred IUPAC name
4-Chloro-3-methylphenol
Other names
p-chloro-m-cresol; PCMC; Preventol; CMK
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.392
EC Number
  • 200-431-6
KEGG
RTECS number
  • GO7100000
UNII
UN number 2669
  • InChI=1S/C7H7ClO/c1-5-4-6(9)2-3-7(5)8/h2-4,9H,1H3 Y
    Key: CFKMVGJGLGKFKI-UHFFFAOYSA-N Y
  • InChI=1/C7H7ClO/c1-5-4-6(9)2-3-7(5)8/h2-4,9H,1H3
    Key: CFKMVGJGLGKFKI-UHFFFAOYAE
  • Oc1ccc(Cl)c(C)c1
Properties
C7H7ClO
Molar mass 142.58 g·mol−1
Appearance White solid
Odor Phenolic
Density 1.37 g/cm3 (20 °C)
Melting point 55.55 °C (131.99 °F; 328.70 K)
Boiling point 235 °C (455 °F; 508 K)
3.8 g/L at 20 °C (in water)
Hazards
GHS labelling:
Danger
H302, H314, H317, H335, H400, H412
P260, P261, P264, P270, P271, P272, P273, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P330, P333+P313, P363, P391, P403+P233, P405, P501
Flash point 118 °C (244 °F; 391 K)
Related compounds
Related compounds
Chloroxylenol (4-chloro-3,5-dimethylphenol)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

p-Chlorocresol, or 4-chloro-3-methylphenol (ClC6H3CH3OH), also known as p-chloro-m-cresol, is a potent disinfectant and antiseptic. It appears as a pinkish white crystalline solid. It is also used as a preservative in cosmetics and medicinal products for both humans and animals. It is used as an active ingredient in some preparations of veterinary medicines for topical, oral and parenteral use. Normally, the concentration of p-Chlorocresol in oral and parenteral veterinary products are 0.1-0.2%. Concentrations are higher (~0.5%) in topical veterinary products. p-Chlorocresol contains microbial activity against both gram positive and gram negative bacteria and fungi.

The use of p-Chlorocresol is regulated by government agencies such as the US Food and Drug administration, and limits are set on the amount of p-Chlorocresol that can be present in various products.

Chlorocresol was first introduced as a bactericide in 1897 by Kalle & Co. after scientists gradually discovered that more substituted and more lipophylic phenols are less toxic, less irritant and more powerful.