P4HTM

P4HTM
Identifiers
Aliases	P4HTM, EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4, prolyl 4-hydroxylase, transmembrane, HIDEA
External IDs	OMIM: 614584; MGI: 1921693; HomoloGene: 41765; GeneCards: P4HTM; OMA:P4HTM - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	49,007,153 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	108,474,866 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; bronchial epithelial cell; ; pituitary gland; ; anterior pituitary; ; prefrontal cortex; ; right frontal lobe; ; right hemisphere of cerebellum; ; Brodmann area 9; ; nucleus accumbens; ; anterior cingulate cortex;
	Top expressed in
	substantia nigra; ; nucleus accumbens; ; temporal lobe; ; facial motor nucleus; ; prefrontal cortex; ; ventromedial nucleus; ; central gray substance of midbrain; ; lateral septal nucleus; ; anterior amygdaloid area; ; paraventricular nucleus of hypothalamus;
	More reference expression data
	n/a
Gene ontology
Molecular function	2-oxoglutarate-dependent dioxygenase activity; iron ion binding; L-ascorbic acid binding; oxidoreductase activity; dioxygenase activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; metal ion binding; calcium ion binding; procollagen-proline 4-dioxygenase activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; endoplasmic reticulum; membrane;
Biological process	regulation of erythrocyte differentiation; peptidyl-proline hydroxylation to 4-hydroxy-L-proline;
	Sources:Amigo / QuickGO
Orthologs
	54681
	74443
	ENSG00000178467
	ENSMUSG00000006675
	Q9NXG6
	Q8BG58
	NM_017732; NM_177938; NM_177939
	NM_028944; NM_001357465
	NP_808807; NP_808808
	NP_083220; NP_001344394
	Wikidata
View/Edit Human	View/Edit Mouse

Prolyl 4-hydroxylase, transmembrane is a protein that in humans is encoded by the P4HTM gene.