PABPN1

PABPN1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3B4D, 3B4M, 3UCG
Identifiers
Aliases	PABPN1, OPMD, PAB2, PABII, PABP-2, PABP2, poly(A) binding protein nuclear 1
External IDs	OMIM: 602279; MGI: 1859158; HomoloGene: 3412; GeneCards: PABPN1; OMA:PABPN1 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	23,326,163 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	55,135,626 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; right hemisphere of cerebellum; ; right uterine tube; ; anterior pituitary; ; body of uterus; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; ganglionic eminence; ; sural nerve;
	Top expressed in
	neural layer of retina; ; ventricular zone; ; tail of embryo; ; renal corpuscle; ; superior frontal gyrus; ; genital tubercle; ; primary visual cortex; ; epiblast; ; lip; ; dentate gyrus of hippocampal formation granule cell;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; nucleic acid binding; RNA binding; RNA polymerase binding;
Cellular component	cytoplasm; nucleoplasm; nuclear inclusion body; nucleus; nuclear speck; ribonucleoprotein complex;
Biological process	mRNA splicing, via spliceosome; termination of RNA polymerase II transcription; RNA processing; muscle contraction; mRNA processing; poly(A)+ mRNA export from nucleus; modification by virus of host mRNA processing; mRNA 3'-end processing; MAPK cascade; cellular response to lipopolysaccharide; positive regulation of polynucleotide adenylyltransferase activity;
	Sources:Amigo / QuickGO
Orthologs
	8106
	54196
	ENSG00000100836
	ENSMUSG00000022194
	Q86U42
	Q8CCS6
	NM_004643; NM_001360551; NM_001360552
	NM_019402
	NP_004634; NP_001347480; NP_001347481
	NP_062275
	Wikidata
View/Edit Human	View/Edit Mouse

Polyadenylate-binding protein 2 (PABP-2) also known as polyadenylate-binding nuclear protein 1 (PABPN1) is a protein that in humans is encoded by the PABPN1 gene. PABN1 is a member of a larger family of poly(A)-binding proteins in the human genome.