PAK5

PAK5
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2F57
Identifiers
Aliases	PAK5, PAK7, p21 (RAC1) activated kinase 7, p21 (RAC1) activated kinase 5
External IDs	OMIM: 608038; MGI: 1920334; HomoloGene: 22211; GeneCards: PAK5; OMA:PAK5 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	9,839,076 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	136,229,887 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; ganglionic eminence; ; Brodmann area 23; ; cerebellar vermis; ; endothelial cell; ; primary visual cortex; ; Brodmann area 46; ; buccal mucosa cell; ; cerebellar hemisphere; ; prefrontal cortex;
	Top expressed in
	lumbar subsegment of spinal cord; ; zygote; ; Rostral migratory stream; ; secondary oocyte; ; primary motor cortex; ; primary oocyte; ; retinal pigment epithelium; ; ganglionic eminence; ; primary visual cortex; ; superior frontal gyrus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; kinase activity; ATP binding; protein binding; protein serine/threonine kinase activity;
Cellular component	cytoplasm; mitochondrion; nucleus; nucleoplasm; synapse;
Biological process	locomotory behavior; phosphorylation; negative regulation of extrinsic apoptotic signaling pathway; memory; learning; protein phosphorylation; cytoskeleton organization; cell population proliferation; cell migration; signal transduction; apoptotic process; Rho protein signal transduction; regulation of mitotic cell cycle; actin cytoskeleton organization; stress-activated protein kinase signaling cascade; activation of protein kinase activity; regulation of apoptotic process; regulation of MAPK cascade; cell growth; regulation of cell growth;
	Sources:Amigo / QuickGO
Orthologs
	57144
	241656
	ENSG00000101349
	ENSMUSG00000039913
	Q9P286
	Q8C015
	NM_020341; NM_177990
	NM_172858; NM_001360382; NM_001360384
	NP_065074; NP_817127
	NP_766446; NP_001347311; NP_001347313
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase PAK 5 is an enzyme that in humans is encoded by the PAK5 gene.

The PAK5 enzyme is one of three members of Group II PAK family of serine/threonine kinases, and evolutionary conserved across species.