PAK6

PAK6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2C30, 2ODB, 4KS8
Identifiers
Aliases	PAK6, PAK5, p21 (RAC1) activated kinase 6
External IDs	OMIM: 608110; MGI: 2679420; HomoloGene: 23200; GeneCards: PAK6; OMA:PAK6 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	40,277,487 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	118,528,501 bp
RNA expression pattern
	Top expressed in
	gingival epithelium; ; entorhinal cortex; ; right frontal lobe; ; skin of thigh; ; prefrontal cortex; ; postcentral gyrus; ; mucosa of esophagus; ; skin of abdomen; ; superior frontal gyrus; ; anterior cingulate cortex;
	Top expressed in
	lumbar subsegment of spinal cord; ; dentate gyrus of hippocampal formation granule cell; ; piriform cortex; ; superior frontal gyrus; ; primary visual cortex; ; lip; ; Region I of hippocampus proper; ; olfactory tubercle; ; cingulate gyrus; ; lateral septal nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein kinase activity; kinase activity; protein binding; ATP binding; cadherin binding; protein serine/threonine kinase activity;
Cellular component	cytoplasm; fibrillar center; nucleus; cell junction;
Biological process	regulation of transcription, DNA-templated; phosphorylation; protein phosphorylation; cytoskeleton organization; apoptotic process; Rho protein signal transduction; regulation of mitotic cell cycle; cell migration; signal transduction; actin cytoskeleton organization; stress-activated protein kinase signaling cascade; activation of protein kinase activity; regulation of apoptotic process; regulation of MAPK cascade;
	Sources:Amigo / QuickGO
Orthologs
	56924
	214230
	ENSG00000137843
	ENSMUSG00000074923
	Q9NQU5
	Q3ULB5
	NM_020168; NM_001276717; NM_001276718; NM_001395430; NM_001395431
	NM_001033254; NM_001145854
	NP_001122100; NP_001122101
	NP_001028426; NP_001139326
	Wikidata
View/Edit Human	View/Edit Mouse

Serine/threonine-protein kinase PAK 6 is an enzyme that in humans is encoded by the PAK6 gene.

PAK6 belongs to the Group II PAK family members. Like other family members, PAK6 is also evolutionary conserved across species.