Pappalysin-2

PAPPA2
Identifiers
Aliases	PAPPA2, PAPP-A2, PAPP-E, PAPPE, PLAC3, pappalysin 2, SSDA
External IDs	MGI: 3051647; HomoloGene: 10661; GeneCards: PAPPA2; OMA:PAPPA2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	176,845,601 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	158,808,060 bp
RNA expression pattern
	Top expressed in
	decidua; ; islet of Langerhans; ; cartilage tissue; ; ventricular zone; ; buccal mucosa cell; ; testicle; ; ganglionic eminence; ; human kidney; ; pancreatic ductal cell; ; stromal cell of endometrium;
	Top expressed in
	calvaria; ; islet of Langerhans; ; lumbar spinal ganglion; ; pituitary gland; ; pontine nuclei; ; trigeminal ganglion; ; dermis; ; lobe of prostate; ; efferent ductule; ; condyle;
	More reference expression data
	n/a
Gene ontology
Molecular function	zinc ion binding; peptidase activity; hydrolase activity; metallopeptidase activity; metal ion binding; metalloendopeptidase activity;
Cellular component	extracellular region; extracellular exosome; intracellular anatomical structure; cytosol; apical plasma membrane;
Biological process	bone morphogenesis; regulation of cell growth; proteolysis; response to salt stress;
	Sources:Amigo / QuickGO
Orthologs
	60676
	23850
	ENSG00000116183
	ENSMUSG00000073530
	Q9BXP8
	n/a
	NM_020318; NM_021936
	NM_001085376
	NP_064714; NP_068755
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Pappalysin-2 also known as pregnancy-associated plasma protein A2 (PAPP-A2) is a protein that in humans is encoded by the PAPPA2 gene.