PARP2

PARP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3KCZ, 3KJD, 4PJV, 4TVJ, 4ZZX, 4ZZY, 5DSY, 5D5K
Identifiers
Aliases	PARP2, ADPRT2, ADPRTL2, ADPRTL3, ARTD2, PARP-2, pADPRT-2, poly(ADP-ribose) polymerase 2
External IDs	OMIM: 607725; MGI: 1341112; HomoloGene: 4004; GeneCards: PARP2; OMA:PARP2 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	20,357,904 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	51,058,758 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; right frontal lobe; ; Brodmann area 9; ; gonad; ; ventricular zone; ; ganglionic eminence; ; prefrontal cortex; ; cerebellar vermis; ; left ovary;
	Top expressed in
	tail of embryo; ; Ileal epithelium; ; genital tubercle; ; neural layer of retina; ; otic placode; ; epiblast; ; ventricular zone; ; embryo; ; primitive streak; ; embryo;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	transferase activity; DNA binding; protein binding; DNA ligase (ATP) activity; glycosyltransferase activity; NAD+ ADP-ribosyltransferase activity; protein ADP-ribosylase activity; NAD DNA ADP-ribosyltransferase activity;
Cellular component	cytoplasm; nucleolus; nucleus; nucleoplasm;
Biological process	DNA ligation involved in DNA repair; lagging strand elongation; protein ADP-ribosylation; DNA repair; extrinsic apoptotic signaling pathway; base-excision repair; peptidyl-serine ADP-ribosylation; positive regulation of cell growth involved in cardiac muscle cell development; negative regulation of neuron death; double-strand break repair; protein poly-ADP-ribosylation; DNA ADP-ribosylation; cellular response to DNA damage stimulus;
	Sources:Amigo / QuickGO
Orthologs
	10038
	11546
	ENSG00000129484
	ENSMUSG00000036023
	Q9UGN5
	O88554
	NM_001042618; NM_005484
	NM_009632
	NP_001036083; NP_005475
	NP_033762
	Wikidata
View/Edit Human	View/Edit Mouse

Poly [ADP-ribose] polymerase 2 is an enzyme that in humans is encoded by the PARP2 gene. It is one of the PARP family of enzymes.