PASK

PASK
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1LL8, 3DLS
Identifiers
Aliases	PASK, PASKIN, STK37, PAS domain containing serine/threonine kinase
External IDs	OMIM: 607505; MGI: 2155936; HomoloGene: 9038; GeneCards: PASK; OMA:PASK - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	241,150,264 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	93,271,204 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; oocyte; ; right testis; ; left testis; ; secondary oocyte; ; lymph node; ; appendix; ; caudate nucleus; ; putamen; ; nucleus accumbens;
	Top expressed in
	spermatocyte; ; spermatid; ; otic vesicle; ; otic placode; ; saccule; ; seminiferous tubule; ; epiblast; ; ventricular zone; ; tail of embryo; ; gastrula;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	kinase activity; transferase activity; nucleotide binding; protein kinase activity; protein binding; ATP binding; phosphatidylinositol binding; lipid binding; protein serine/threonine kinase activity;
Cellular component	nucleus; cytosol; cytoplasm;
Biological process	regulation of respiratory gaseous exchange; protein autophosphorylation; negative regulation of glycogen biosynthetic process; positive regulation of translation; regulation of glucagon secretion; phosphorylation; protein phosphorylation; energy homeostasis; intracellular signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	23178
	269224
	ENSG00000115687
	ENSMUSG00000026274
	Q96RG2
	Q8CEE6
	NM_001252119; NM_001252120; NM_001252122; NM_001252124; NM_015148
	NM_080850
	NP_001239048; NP_001239049; NP_001239051; NP_001239053; NP_055963
	NP_543126
	Wikidata
View/Edit Human	View/Edit Mouse

PAS domain-containing serine/threonine-protein kinase is an enzyme that in humans is encoded by the PASK gene.

PAS domains regulate the function of many intracellular signaling pathways in response to both extrinsic and intrinsic stimuli. PASK is an evolutionarily conserved protein present in yeast, flies, and mammals.[supplied by OMIM]