PCLO

PCLO
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1UJD
Identifiers
Aliases	PCLO, ACZ, PCH3, piccolo presynaptic cytomatrix protein
External IDs	OMIM: 604918; MGI: 1349390; HomoloGene: 69111; GeneCards: PCLO; OMA:PCLO - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	83,162,930 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	14,913,473 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; middle temporal gyrus; ; cerebellar vermis; ; orbitofrontal cortex; ; Region I of hippocampus proper; ; endothelial cell; ; frontal pole; ; entorhinal cortex; ; Brodmann area 46; ; superior frontal gyrus;
	Top expressed in
	cingulate gyrus; ; primary motor cortex; ; prefrontal cortex; ; subiculum; ; medial dorsal nucleus; ; temporal lobe; ; Amygdala; ; superior cervical ganglion; ; olfactory tubercle; ; piriform cortex;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	calcium-dependent phospholipid binding; profilin binding; calcium ion binding; metal ion binding; structural constituent of presynaptic active zone;
Cellular component	presynaptic active zone; cell junction; synapse; cytoskeleton; extracellular exosome; membrane; postsynaptic density; cytoskeleton of presynaptic active zone; presynaptic active zone cytoplasmic component;
Biological process	regulation of exocytosis; synapse assembly; insulin secretion; cytoskeleton organization; cAMP-mediated signaling; synaptic vesicle exocytosis; protein localization to synapse; presynapse to nucleus signaling pathway; maintenance of presynaptic active zone structure; synaptic vesicle clustering;
	Sources:Amigo / QuickGO
Orthologs
	27445
	26875
	ENSG00000186472
	ENSMUSG00000061601
	Q9Y6V0
	Q9QYX7
	NM_033026; NM_014510
	NM_001110796; NM_011995
	NP_055325; NP_149015
	NP_001104266; NP_036125
	Wikidata
View/Edit Human	View/Edit Mouse

Protein piccolo is a protein that in humans is encoded by the PCLO gene.