PDCD7

PDCD7
Identifiers
Aliases	PDCD7, ES18, HES18, programmed cell death 7, 59K
External IDs	OMIM: 608138; MGI: 1859170; HomoloGene: 4170; GeneCards: PDCD7; OMA:PDCD7 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	65,133,808 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	65,266,925 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; buccal mucosa cell; ; nipple; ; superior surface of tongue; ; tendon of biceps brachii; ; thymus; ; external globus pallidus; ; nasal epithelium; ; tail of epididymis; ; Medulla Oblongata;
	Top expressed in
	primary oocyte; ; secondary oocyte; ; zygote; ; spermatocyte; ; neural layer of retina; ; muscle of thigh; ; epiblast; ; soleus muscle; ; genital tubercle; ; corneal stroma;
	More reference expression data
	n/a
Orthologs
	10081
	50996
	ENSG00000090470
	ENSMUSG00000041837
	Q8N8D1
	Q9WTY1
	NM_005707
	NM_016688
	NP_005698
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Programmed cell death protein 7 is a protein that in humans is encoded by the PDCD7 gene.

This gene encodes a protein with sequence similarity to a mouse protein originally identified in embryonic stem cells. In mouse T-cell lines, this protein appears to be related to glucocorticoid- and staurine-induced apoptotic pathways, and to be linked to ceramide-mediated signalling. These observations suggest that this gene product is involved in specific apoptotic processes in T-cells.