Phosducin-like

PDCL
Identifiers
Aliases	PDCL, PhLP, Phosducin-like, phosducin like
External IDs	OMIM: 604421; MGI: 1914716; HomoloGene: 38043; GeneCards: PDCL; OMA:PDCL - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	122,828,588 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	37,249,344 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; endothelial cell; ; visceral pleura; ; oocyte; ; parietal pleura; ; tibia; ; Achilles tendon; ; secondary oocyte; ; germinal epithelium; ; epithelium of nasopharynx;
	Top expressed in
	pineal gland; ; cumulus cell; ; neural layer of retina; ; medial ganglionic eminence; ; stria vascularis; ; carotid body; ; superior cervical ganglion; ; vestibular sensory epithelium; ; mandibular prominence; ; maxillary prominence;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; queuine tRNA-ribosyltransferase activity; protein-containing complex binding;
Cellular component	cytoplasm; cytosol; cilium; cell projection;
Biological process	queuosine biosynthetic process; heterotrimeric G-protein complex assembly; regulation of G protein-coupled receptor signaling pathway; negative regulation of protein refolding; signal transduction; visual perception; response to stimulus; protein folding; positive regulation of smoothened signaling pathway; cell projection organization;
	Sources:Amigo / QuickGO
Orthologs
	5082
	67466
	ENSG00000136940
	ENSMUSG00000009030
	Q13371
	Q9DBX2
	NM_005388
	NM_026176
	NP_005379
	NP_080452
	Wikidata
View/Edit Human	View/Edit Mouse

Phosducin-like protein is a protein that in humans is encoded by the PDCL gene.

Phosducin-like protein is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin, a phosphoprotein expressed in the retina and pineal gland. Both phosducin-like protein and phosphoducin have been shown to regulate G-protein signaling by binding to the beta-gamma subunits of G proteins.