PDE1C

PDE1C
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1LXS
Identifiers
Aliases	PDE1C, Hcam3, cam-PDE 1C, hCam-3, phosphodiesterase 1C, DFNA74
External IDs	OMIM: 602987; MGI: 108413; HomoloGene: 3682; GeneCards: PDE1C; OMA:PDE1C - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	32,428,131 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	56,629,472 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; right ventricle; ; corpus callosum; ; apex of heart; ; left ventricle; ; sural nerve; ; inferior ganglion of vagus nerve; ; external globus pallidus; ; internal globus pallidus; ; right auricle of heart;
	Top expressed in
	lumbar spinal ganglion; ; spermatocyte; ; spermatid; ; retinal pigment epithelium; ; supraoptic nucleus; ; aortic valve; ; ascending aorta; ; ciliary body; ; iris; ; olfactory epithelium;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	phosphoric diester hydrolase activity; calmodulin-dependent cyclic-nucleotide phosphodiesterase activity; hydrolase activity; 3',5'-cyclic-nucleotide phosphodiesterase activity; metal ion binding; calmodulin binding; calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity; 3',5'-cyclic-GMP phosphodiesterase activity;
Cellular component	cytosol; soma;
Biological process	signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	5137
	18575
	ENSG00000154678
	ENSMUSG00000004347
	Q14123
	Q64338
NM_001191056; NM_001191057; NM_001191058; NM_001191059; NM_005020;
	NM_001322055; NM_001322056; NM_001322057; NM_001322058; NM_001322059
NM_001025568; NM_001159952; NM_001159953; NM_001159955; NM_001159956;
	NM_001159957; NM_001159960; NM_011054; NM_001355475
NP_001177985; NP_001177986; NP_001177987; NP_001177988; NP_001308984;
	NP_001308985; NP_001308986; NP_001308987; NP_001308988; NP_005011
NP_001020739; NP_001153424; NP_001153425; NP_001153427; NP_001153428;
	NP_001153429; NP_001153432; NP_035184; NP_001342404
	Wikidata
View/Edit Human	View/Edit Mouse

Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C is an enzyme that in humans is encoded by the PDE1C gene.