Peflin

PEF1
Identifiers
Aliases	PEF1, ABP32, PEF1A, penta-EF-hand domain containing 1
External IDs	OMIM: 610033; MGI: 1915148; HomoloGene: 56569; GeneCards: PEF1; OMA:PEF1 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	31,644,896 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	130,021,928 bp
RNA expression pattern
	Top expressed in
	left lobe of thyroid gland; ; right lobe of thyroid gland; ; ascending aorta; ; skin of leg; ; skin of abdomen; ; popliteal artery; ; tibial arteries; ; Descending thoracic aorta; ; right coronary artery; ; left coronary artery;
	Top expressed in
	granulocyte; ; right kidney; ; duodenum; ; lip; ; facial motor nucleus; ; proximal tubule; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; esophagus; ; muscle of thigh;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; protein binding; protein dimerization activity; metal ion binding; calcium-dependent cysteine-type endopeptidase activity; protein heterodimerization activity; RNA binding; calcium-dependent protein binding; molecular adaptor activity;
Cellular component	cytoplasm; extracellular exosome; membrane; Golgi membrane; COPII vesicle coat; Cul3-RING ubiquitin ligase complex; endoplasmic reticulum; ER to Golgi transport vesicle membrane; cytoplasmic vesicle;
Biological process	response to calcium ion; proteolysis; endoplasmic reticulum to Golgi vesicle-mediated transport; neural crest formation; neural crest cell development; COPII vesicle coating; positive regulation of protein monoubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	553115
	67898
	ENSG00000162517
	ENSMUSG00000028779
	Q9UBV8
	Q8BFY6
	NM_012392; NM_001359651
	NM_026441
	NP_036524; NP_001346580
	NP_080717
	Wikidata
View/Edit Human	View/Edit Mouse

Peflin is a protein that in humans is encoded by the PEF1 gene.

PEF1 is a Ca(2+)-binding protein that belongs to the penta-EF hand (PEF) protein family, which includes the calpain small subunit (CAPNS1; MIM 114170), sorcin (SRI; MIM 182520), grancalcin (GCA; MIM 607030), and ALG2 (PDCD6; MIM 601057) (Kitaura et al., 2001).[supplied by OMIM]