PER2

PER2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3GDI, 4CT0, 4U8H
Identifiers
Aliases	PER2, FASPS, FASPS1, period circadian clock 2, period circadian regulator 2
External IDs	OMIM: 603426; MGI: 1195265; HomoloGene: 7885; GeneCards: PER2; OMA:PER2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	238,290,102 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	91,387,046 bp
RNA expression pattern
	Top expressed in
	oocyte; ; mucosa of paranasal sinus; ; secondary oocyte; ; bronchial epithelial cell; ; palpebral conjunctiva; ; nasal epithelium; ; tail of epididymis; ; urethra; ; caput epididymis; ; skin of thigh;
	Top expressed in
	adrenal gland; ; left lung lobe; ; suprachiasmatic nucleus; ; granulocyte; ; rectum; ; lacrimal gland; ; median eminence; ; primary motor cortex; ; lobe of cerebellum; ; respiratory epithelium;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	transcription coactivator activity; transcription cis-regulatory region binding; protein binding; transcription corepressor binding; transcription factor binding;
Cellular component	nucleolus; perinuclear region of cytoplasm; nucleus; cytoplasm;
Biological process	histone H3 deacetylation; gluconeogenesis; regulation of transcription, DNA-templated; regulation of insulin secretion; rhythmic process; negative regulation of fat cell proliferation; negative regulation of circadian rhythm; negative regulation of transcription by RNA polymerase II; circadian regulation of gene expression; transcription, DNA-templated; fatty acid metabolic process; regulation of cell cycle; negative regulation of protein ubiquitination; circadian regulation of translation; response to ischemia; regulation of vasoconstriction; glycogen biosynthetic process; negative regulation of transcription regulatory region DNA binding; regulation of circadian rhythm; circadian rhythm; white fat cell differentiation; regulation of glutamate uptake involved in transmission of nerve impulse; lactate biosynthetic process; negative regulation of transcription, DNA-templated; regulation of neurogenesis; positive regulation of nucleic acid-templated transcription; response to light stimulus; entrainment of circadian clock by photoperiod; positive regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologs
	8864
	18627
	ENSG00000132326
	ENSMUSG00000055866
	O15055
	O54943
	NM_003894; NM_022817
	NM_011066
	NP_073728
	NP_035196
	Wikidata
View/Edit Human	View/Edit Mouse

PER2 is a protein in mammals encoded by the PER2 gene. PER2 is noted for its major role in circadian rhythms.