PEX6

PEX6
Identifiers
Aliases	PEX6, PAF-2, PAF2, PBD4A, PDB4B, PXAAA1, HMLR2, peroxisomal biogenesis factor 6
External IDs	OMIM: 601498; MGI: 2385054; HomoloGene: 47914; GeneCards: PEX6; OMA:PEX6 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	42,979,181 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	47,036,467 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; body of pancreas; ; mucosa of transverse colon; ; right hemisphere of cerebellum; ; right lobe of liver; ; anterior pituitary; ; right ovary; ; left ovary; ; right frontal lobe; ; right adrenal gland;
	Top expressed in
	Rostral migratory stream; ; internal carotid artery; ; left lobe of liver; ; external carotid artery; ; brown adipose tissue; ; ciliary body; ; transitional epithelium of urinary bladder; ; motor neuron; ; Paneth cell; ; vas deferens;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; protein C-terminus binding; ATPase activity; protein binding; ATP binding; protein-containing complex binding;
Cellular component	cytoplasm; peroxisomal membrane; peroxisome; membrane; photoreceptor cell cilium; photoreceptor outer segment; cell projection; cytosol;
Biological process	protein stabilization; peroxisome organization; protein import into peroxisome matrix, translocation; protein targeting to peroxisome; protein import into peroxisome matrix;
	Sources:Amigo / QuickGO
Orthologs
	5190
	224824
	ENSG00000124587
	ENSMUSG00000002763
	Q13608
	Q99LC9
	NM_000287; NM_001316313
	NM_145488
	NP_000278; NP_001303242
	NP_663463
	Wikidata
View/Edit Human	View/Edit Mouse

Peroxisome assembly factor 2 is a protein that in humans is encoded by the PEX6 gene. PEX6 is an AAA ATPase that localizes to the peroxisome. PEX6 forms a hexamer with PEX1 and is recruited to the membrane by PEX26.