Periodic fever, aphthous stomatitis, pharyngitis and adenitis

Periodic fever, aphthous stomatitis, pharyngitis and adenitis
Other namesPeriodic fever aphthous pharyngitis and cervical adenopathy (PFAPA)
SpecialtyPediatric, Rheumatology, Immunology
SymptomsFever recurring on a ~2–6 week cycle
TreatmentTonsillectomy
MedicationCorticosteroids, Colchicine, Cimetidine

Periodic fever, aphthous stomatitis, pharyngitis and adenitis syndrome is a medical condition, typically occurring in young children, in which high fever occurs periodically at intervals of about 3–5 weeks, frequently accompanied by aphthous-like ulcers, pharyngitis and cervical adenitis (cervical lymphadenopathy). The syndrome was described in 1987 and named two years later.

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