PFKFB4

PFKFB4
Identifiers
Aliases	PFKFB4, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
External IDs	OMIM: 605320; MGI: 2687284; HomoloGene: 48288; GeneCards: PFKFB4; OMA:PFKFB4 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	48,562,015 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	108,861,296 bp
RNA expression pattern
	Top expressed in
	blood; ; monocyte; ; right testis; ; left testis; ; stromal cell of endometrium; ; granulocyte; ; jejunal mucosa; ; gonad; ; duodenum; ; body of pancreas;
	Top expressed in
	granulocyte; ; muscle of thigh; ; spermatocyte; ; vastus lateralis muscle; ; triceps brachii muscle; ; knee joint; ; jejunum; ; gastrula; ; duodenum; ; skeletal muscle tissue;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; fructose-2,6-bisphosphate 2-phosphatase activity; catalytic activity; hydrolase activity; ATP binding; kinase activity; 6-phosphofructo-2-kinase activity;
Cellular component	cytosol;
Biological process	fructose metabolic process; metabolism; fructose 2,6-bisphosphate metabolic process; phosphorylation; dephosphorylation; carbohydrate phosphorylation; positive regulation of glycolytic process;
	Sources:Amigo / QuickGO
Orthologs
	5210
	270198
	ENSG00000114268
	ENSMUSG00000025648
	Q16877
	Q6DTY7
NM_004567; NM_001317134; NM_001317135; NM_001317136; NM_001317137;
	NM_001317138
	NM_001039215; NM_001039216; NM_001039217; NM_173019
NP_001304063; NP_001304064; NP_001304065; NP_001304066; NP_001304067;
	NP_004558
	NP_766607
	Wikidata
View/Edit Human	View/Edit Mouse

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 also known as PFKFB4 is an enzyme which in humans is encoded by the PFKFB4 gene.