Peptidoglycan recognition protein 4

PGLYRP4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2EAV, 2EAX
Identifiers
Aliases	PGLYRP4, PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67, peptidoglycan recognition protein 4
External IDs	OMIM: 608198; MGI: 2686324; HomoloGene: 130057; GeneCards: PGLYRP4; OMA:PGLYRP4 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	153,348,841 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	90,648,824 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; skin of leg; ; skin of thigh; ; cervix epithelium; ; tibialis anterior muscle; ; mucosa of ileum; ; pancreatic ductal cell; ; vagina; ; human penis; ; vulva;
	Top expressed in
	esophagus; ; lip; ; granulocyte; ; zone of skin; ; spermatocyte; ; thymus; ; spermatid; ; testicle; ; spleen; ; stomach;
	More reference expression data
	n/a
Gene ontology
Molecular function	zinc ion binding; N-acetylmuramoyl-L-alanine amidase activity; peptidoglycan immune receptor activity; peptidoglycan binding; protein heterodimerization activity;
Cellular component	extracellular region; intracellular anatomical structure; membrane; protein-containing complex; extracellular space;
Biological process	immune system process; innate immune response; defense response to bacterium; detection of bacterium; defense response to Gram-positive bacterium; peptidoglycan catabolic process; pattern recognition receptor signaling pathway; positive regulation of cytolysis in other organism; antimicrobial humoral immune response mediated by antimicrobial peptide; antimicrobial humoral response; killing of cells of other organism; negative regulation of interferon-gamma production; negative regulation of natural killer cell differentiation involved in immune response;
	Sources:Amigo / QuickGO
Orthologs
	57115
	384997
	ENSG00000163218
	ENSMUSG00000042250
	Q96LB8
	Q0VB07
	NM_020393
	NM_001165968; NM_207263
	NP_065126
	NP_001159440; NP_997146
	Wikidata
View/Edit Human	View/Edit Mouse

Peptidoglycan recognition protein 4 (PGLYRP4, formerly PGRP-Iβ) is an antibacterial and anti-inflammatory innate immunity protein that in humans is encoded by the PGLYRP4 gene.