PHF1

PHF1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2E5P, 2M0O, 4HCZ
Identifiers
Aliases	PHF1, MTF2L2, PCL1, PHF2, TDRD19C, hPHD finger protein 1
External IDs	OMIM: 602881; MGI: 98647; HomoloGene: 7567; GeneCards: PHF1; OMA:PHF1 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	33,416,453 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	27,156,882 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; pituitary gland; ; anterior pituitary; ; left ovary; ; right ovary; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; canal of the cervix; ; gastric mucosa;
	Top expressed in
	granulocyte; ; zygote; ; spermatocyte; ; secondary oocyte; ; primary oocyte; ; spermatid; ; neural layer of retina; ; ankle joint; ; seminiferous tubule; ; entorhinal cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; metal ion binding; methylated histone binding; protein binding; chromatin binding; nucleosome binding; sequence-specific DNA binding;
Cellular component	cytoplasm; site of double-strand break; ESC/E(Z) complex; nucleoplasm; microtubule organizing center; cytoskeleton; nucleus; centrosome;
Biological process	negative regulation of histone H3-K27 methylation; regulation of transcription, DNA-templated; transcription, DNA-templated; cellular response to DNA damage stimulus; regulation of histone methylation; negative regulation of gene expression, epigenetic; positive regulation of histone H3-K27 methylation; chromatin organization; positive regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	5252
	21652
	ENSG00000112511; ENSG00000225553; ENSG00000239756
	ENSMUSG00000024193
	O43189
	Q9Z1B8
	NM_002636; NM_024165
	NM_009343; NM_001302397
	NP_002627; NP_077084
	NP_001289326; NP_033369
	Wikidata
View/Edit Human	View/Edit Mouse

PHD finger protein 1 is a protein that in humans is encoded by the PHF1 gene.