PHF6

PHF6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4NN2, 4R7A
Identifiers
Aliases	PHF6, BFLS, BORJ, CENP-31, PHD finger protein 6
External IDs	OMIM: 300414; MGI: 1918248; HomoloGene: 12375; GeneCards: PHF6; OMA:PHF6 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	134,428,791 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	52,045,820 bp
RNA expression pattern
	Top expressed in
	corpus epididymis; ; oocyte; ; endothelial cell; ; germinal epithelium; ; secondary oocyte; ; ganglionic eminence; ; pancreatic epithelial cell; ; palpebral conjunctiva; ; epithelium of nasopharynx; ; Brodmann area 23;
	Top expressed in
	hand; ; superior cervical ganglion; ; ventricular zone; ; genital tubercle; ; tail of embryo; ; medial ganglionic eminence; ; zygote; ; epiblast; ; maxillary prominence; ; trigeminal ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	tubulin binding; enzyme binding; scaffold protein binding; DNA binding; ribonucleoprotein complex binding; histone binding; phosphoprotein binding; histone deacetylase binding; protein binding; metal ion binding; RNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; sequence-specific DNA binding;
Cellular component	nucleolus; chromosome, centromeric region; nucleus; kinetochore; nucleoplasm; chromosome;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; blastocyst hatching;
	Sources:Amigo / QuickGO
Orthologs
	84295
	70998
	ENSG00000156531
	ENSMUSG00000025626
	Q8IWS0
	Q9D4J7
	NM_032458; NM_001015877; NM_032335
	NM_001290546; NM_027642
	NP_001015877; NP_115711; NP_115834
	NP_001277475; NP_081918
	Wikidata
View/Edit Human	View/Edit Mouse

PHD finger protein 6 is a protein that in humans is encoded by the PHF6 gene.

This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two atypical PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus.