PHLDA1

PHLDA1
Identifiers
Aliases	PHLDA1, DT1P1B11, PHRIP, TDAG51, pleckstrin homology like domain family A member 1
External IDs	OMIM: 605335; MGI: 1096880; HomoloGene: 7203; GeneCards: PHLDA1; OMA:PHLDA1 - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	76,031,776 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	111,344,506 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; stromal cell of endometrium; ; ganglionic eminence; ; salivary gland; ; minor salivary glands; ; gallbladder; ; vagina; ; right lung; ; tibial nerve; ; upper lobe of left lung;
	Top expressed in
	parotid gland; ; submandibular gland; ; lacrimal gland; ; left lobe of liver; ; otic placode; ; lactiferous gland; ; crypt of lieberkuhn of small intestine; ; epithelium of stomach; ; granulocyte; ; stria vascularis;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	cytoplasm; cytoplasmic vesicle; cytosol; nucleus; nucleolus;
Biological process	apoptotic process; FasL biosynthetic process; G2/M transition of mitotic cell cycle;
	Sources:Amigo / QuickGO
Orthologs
	22822
	21664
	ENSG00000139289
	ENSMUSG00000020205
	Q8WV24
	Q62392
	NM_007350
	NM_009344
	NP_031376
	NP_033370
	Wikidata
View/Edit Human	View/Edit Mouse

Pleckstrin homology-like domain family A member 1 (PHLDA1) is a protein that in humans is encoded by the PHLDA1 gene.

This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.