PIAS3

PIAS3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4MVT
Identifiers
Aliases	PIAS3, ZMIZ5, protein inhibitor of activated STAT 3
External IDs	OMIM: 605987; MGI: 1913126; HomoloGene: 4447; GeneCards: PIAS3; OMA:PIAS3 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	145,859,836 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	96,613,386 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; canal of the cervix; ; Descending thoracic aorta; ; right coronary artery; ; ectocervix; ; body of uterus; ; ascending aorta; ; left uterine tube; ; gastric mucosa; ; popliteal artery;
	Top expressed in
	neural layer of retina; ; granulocyte; ; ankle joint; ; lip; ; otic vesicle; ; molar; ; lens; ; genital tubercle; ; yolk sac; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein N-terminus binding; zinc ion binding; metal ion binding; potassium channel regulator activity; protein C-terminus binding; protein binding; enzyme binding; SUMO transferase activity; transferase activity;
Cellular component	cytoplasm; nuclear speck; synapse; nucleoplasm; dendrite; nucleus;
Biological process	negative regulation of protein sumoylation; regulation of transcription, DNA-templated; positive regulation of protein sumoylation; protein sumoylation; transcription, DNA-templated; positive regulation of gene expression; response to hormone; positive regulation of membrane potential; negative regulation of transcription by RNA polymerase II; negative regulation of gene expression; negative regulation of osteoclast differentiation; negative regulation of transcription, DNA-templated; TNFSF11-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	10401
	229615
	ENSG00000131788
	ENSMUSG00000028101
	Q9Y6X2
	O54714
	NM_006099
	NM_001165949; NM_018812; NM_146135
	NP_006090
	NP_001159421; NP_061282; NP_666247
	Wikidata
View/Edit Human	View/Edit Mouse

E3 SUMO-protein ligase PIAS3 is an enzyme that in humans is encoded by the PIAS3 gene.