PICK1

PICK1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2GZV
Identifiers
Aliases	PICK1, PICK, PRKCABP, protein interacting with PRKCA 1
External IDs	OMIM: 605926; MGI: 894645; HomoloGene: 7470; GeneCards: PICK1; OMA:PICK1 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	38,075,701 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	79,133,684 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; right hemisphere of cerebellum; ; right uterine tube; ; left ovary; ; right frontal lobe; ; left testis; ; right testis; ; gastric mucosa; ; right ovary; ; body of pancreas;
	Top expressed in
	neural layer of retina; ; spermatid; ; muscle of thigh; ; spermatocyte; ; superior frontal gyrus; ; right kidney; ; lip; ; crypt of lieberkuhn of small intestine; ; extensor digitorum longus muscle; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein domain specific binding; Arp2/3 complex binding; metal ion binding; actin filament binding; protein C-terminus binding; protein binding; identical protein binding; enzyme binding; actin binding; signaling receptor binding; G protein-coupled receptor binding; protein kinase C binding; phospholipid binding;
Cellular component	cytoplasm; endocytic vesicle membrane; postsynaptic membrane; Golgi apparatus; postsynaptic density; membrane; plasma membrane; synapse; cell junction; perinuclear region of cytoplasm; neuron projection; cytoskeleton; presynaptic membrane; mitochondrion; cytosol; aggresome; synaptic vesicle; trans-Golgi network membrane; postsynaptic early endosome;
Biological process	cellular response to glucose starvation; glial cell development; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; positive regulation of receptor internalization; neuronal ion channel clustering; regulation of Arp2/3 complex-mediated actin nucleation; monoamine transport; receptor clustering; DNA methylation involved in gamete generation; negative regulation of Arp2/3 complex-mediated actin nucleation; dendritic spine organization; dendritic spine maintenance; protein phosphorylation; protein kinase C-activating G protein-coupled receptor signaling pathway; long-term depression; cellular response to decreased oxygen levels; DNA methylation involved in embryo development; intracellular protein transport;
	Sources:Amigo / QuickGO
Orthologs
	9463
	18693
	ENSG00000100151
	ENSMUSG00000068206
	Q9NRD5
	Q62083
	NM_001039583; NM_001039584; NM_012407
	NM_001045558; NM_008837
NP_001034672; NP_001034673; NP_036539; NP_001034672.1; NP_001034673.1;
	NP_036539.1
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Protein Interacting with C Kinase - 1 is a protein that in humans is encoded by the PICK1 gene.