PINX1

PINX1
Identifiers
Aliases	PINX1, LPTL, LPTS, PIN2/TERF1 interacting, telomerase inhibitor 1, Gno1, Pxr1, PIN2/TERF1 interacting telomerase inhibitor 1, PIN2 (TERF1) interacting telomerase inhibitor 1
External IDs	OMIM: 606505; MGI: 1919650; HomoloGene: 134540; GeneCards: PINX1; OMA:PINX1 - orthologs
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	64,157,308 bp
Gene ontology
Molecular function	protein binding; nucleic acid binding; telomerase RNA binding; telomerase inhibitor activity; protein-containing complex binding;
Cellular component	spindle; chromosome; nuclear chromosome; chromosome, centromeric region; kinetochore; nucleolus; nucleus; telomere;
Biological process	positive regulation of protein localization to nucleolus; negative regulation of telomere maintenance via telomerase; regulation of protein stability; protein localization to nucleolus; regulation of telomerase activity; protein localization to chromosome, telomeric region; positive regulation of telomeric DNA binding; negative regulation of protein ubiquitination; negative regulation of telomere maintenance via telomere lengthening; mitotic metaphase plate congression; negative regulation of cell population proliferation; negative regulation of telomerase activity; negative regulation of G2/M transition of mitotic cell cycle; telomere maintenance via telomerase;
	Sources:Amigo / QuickGO
Orthologs
	54984
	72400
	ENSG00000254093
	ENSMUSG00000021958
	Q96BK5
	Q9CZX5
	NM_017884; NM_001284356
	NM_028228
	NP_001271285; NP_060354
	NP_082504
	Wikidata
View/Edit Human	View/Edit Mouse

PIN2/TERF1-interacting telomerase inhibitor 1, also known as PINX1, is a human gene. PINX1 is also known as PIN2 interacting protein 1. PINX1 is a telomerase inhibitor and a possible tumor suppressor.